Continued from Part 1. If both copies of the gene are mutated, then each gene can make the right protein about 5 to 10% of the time. Affected Dobermans are thus producing von Willebrand factor Diversity and Recombination In mammals, DNA is not just one continuous strand, but exists within the cell nucleus in a …
By Susan Thorpe-Vargas Ph.D., John Cargill MA, MBA, MS, D. Caroline Coile, Ph.D. Why the dog opted to share his fate with men, may never be known, we suspect it had something to do with filling his stomach, but when he did, mankind took on a moral and ethical obligation. When we started to selectively …
Canine hip Dysplasia (CHD)—the most common orthopedic problem in dogs—is caused by a loose hipbone-thighbone connection. It leads to hind-end pain and lameness that can range from mild to crippling. We know CHD is genetically transmitted. But because multiple genes are involved, scientists have yet to unravel the pattern of inheritance. Adding to the CHD …
Background Friends and fellow dog fanciers: I was asked to comment on some accusations and remarks re HD that have been on chat lists. First, so you understand where I am coming from, you should know a little history of my involvement in dogs, veterinary science, and hip dysplasia in …
The Role of Orthopedic Registries in Fighting Canine Hip Dysplasia; Registries, although essential in documenting CHD, have not been used to their full potential This article is the fourth in an eight-part series on canine hip dysplasia (CHD). What follows is written from the perspective that the readers are serious and conscientious breeders who are …
The authors assess the pros and cons of standard diagnostic methods for hip dysplasia By John C. Cargill, MA MBA, MS and Susan Thorpe-Vargas, MS This article is the third in an eight-part series on canine hip dysplasia (CHD). What follows is written from the perspective that the readers of the series are conscientious breeders …
Causative Factors of Canine Hip Dysplasia Owners must separate fact from myth when examining theories on genetic, nutritional and environmental factors that influence CHD. This is the second part in a series on canine hip dysplasia. What follows is written from the perspective that the readers of the series are conscientious breeders who are the …
Return to Page 1 Your candidate’s Breed Survey should also be scrutinized to learn more about the potential purchase. When the survey was done and when it expires (in the case of a young bitch) are important details. A young female with her first survey under her belt will have to appear again before …
I once had a dog, an expensive dog, she was. An import, yes siree. Superb specimen she was, with an immaculate family tree, starting with a famous father and a mother who in turn was a daughter of another famous one. How could one go wrong? SchH2 KKL1 for life, fertile, beautiful, good hips. I …
“Inbreeding was once a valuable tool in shaping today’s breeds. As these have now reached a high degree of homogeneity, it has lost its importance and turned into a fatal and disastrous habit.” Hellmuth Wachtel, PhD Inbreeding (which, for the purposes of this article, includes “linebreeding”) has been the rule in dog breeding for the …