Guide to Hereditary and Congenital Diseases in Dogs

Published by The Association of Veterinarians for Animal Rights, P.O. Box 208, Davis, CA 95617-0208

First printing: August 1994

Special thanks to: W. Jean Dodds, D.V.M., Susan Hall, D.V.M., Kay Inks, and Phil Maggitti

Directory

Section I

A list of 148 purebred dog breeds, each of which is accompanied by a number or series of numbers that correspond to the genetic diseases identified and described in Section II.’

Section II

An alphabetical listing of genetically transmitted diseases that occur in purebred dogs. Each disease is assigned an identification number, and some diseases are followed by the names of the breeds known to be subject to those diseases.

How to use this book

If you are thinking about acquiring a purebred dog, refer to Section I to find out the number of genetically transmitted diseases associated with the breed or breeds in which you are interested. Refer to Section II to find the names and definitions of those diseases.

Disclaimer

This report was designed to catalogue the existing congenital and hereditary diseases found in purebred dogs and to describe other common conditions that are thought to be genetic in origin because they appear with higher-than-expected frequency in certain breeds. The knowledge of and experience with nonhuman animal diseases is always changing, and new diseases are discovered each year. As a result, this catalogue cannot be fully complete. Every attempt has been made, nevertheless, to provide the latest information from published articles in scientific and popular journals, from review chapters written by veterinary and other professionals, and from breed-club literature provided by designated representatives of individual breed clubs.

The conditions listed in the Canine Consumer Report occur with varying degrees of frequency and severity from one breed to the next. Hip dysplasia, umbilical hernias, and allergies, for example, are common conditions found in many breeds, while serious malformations (such as the lysosomal storage diseases) and life- threatening diseases (such as hemophilia and certain cancers) are found with less frequency. The impact of a particular disorder on the health and longevity of the breed or breeds that it affects will depend on the nature and severity of that disorder. Therefore, no attempt has been made to assign priority among the diseases identified in this catalogue. This sort of information should be sought form veterinarians and other medical professionals with relevant experience and from national breed-club representatives, whose names can be obtained from the American Kennel Club, 51 Madison Avenue, New York, NY 10010.

Section I:

Aberdeen terrier: 324

Affenpinscher: 12, 55, 98, 218, 235, 236, 330

Afghan hound: 14, 42, 65, 96, 114, 121, 135, 145, 147, 166, 206a, 211, 221, 221a, 239, 245, 256, 269, 270, 330

Airedale terrier: 7, 9, 48, 65, 88, 103, 122, 140, 148, 165, 166, 168, 206a, 230, 256, 269, 270, 273a, 314, 318, 330

Akita: 9, 27, 43, 65, 71, 103, 114, 115, 135, 137, 140, 146, 152, 156, 166, 172,192, 193a, 199, 221, 221a, 239, 256, 270, 273a, 312, 318, 329, 330

Alaskan malamute: 13, 42, 59, 65, 67, 85, 89, 120, 121, 122, 135, 144, 147, 148, 150, 152, 166, 206a, 221, 221a, 256, 266, 330, 334

American cocker spaniel: 1, 10, 12, 18, 26, 27, 42, 43, 54, 55, 65, 69, 72, 73, 88, 94, 94a, 95, 103, 107, 109, 121, 123, 135, 146, 147, 148, 152, 154, 166, 171, 173, 179, 181, 186, 188, 193a, 197, 221, 221a, 226, 228, 235, 236, 242, 245, 254, 256, 266, 270, 275, 276, 286, 307, 318, 319, 320, 330

American foxhound: 78, 199, 290, 311

American Staffordshire terrier: 42, 54, 55, 88, 103, 166, 204a, 221, 221a, 256

American water spaniel: 42, 150, 270

Antarctic husky: 103, 147

Australian cattle dog (Australian blue heeler): 42, 78, 109, 121, 124b, 147, 149, 152, 166, 171, 177, 186, 193a, 200, 214, 221, 228, 245, 256, 270, 318, 319

Australian kelpie: 58, 199, 203, 256

Australian shepherd: 42, 55, 58, 78, 89, 152, 166, 199, 203, 221, 221a, 245, 256, 269, 270, 287, 318, 328, 329, 330

Australian terrier: 85, 185, 256, 270

Basenji: 56, 59, 66, 124a, 146, 166, 171, 172, 245, 256, 263, 268, 270, 318

Basset hound: 5, 9, 9a, 15, 27, 31, 61a, 70, 94, 103, 105, 109, 114, 120, 121, 131, 135, 136, 146, 147, 157, 159a, 166, 168, 169, 170, 171, 174, 186, 190, 221, 221a, 222, 231, 235, 245, 249, 256, 274, 291, 299, 311, 318, 330, 332

Beagle: 10, 11, 21, 34, 37, 42, 43, 54, 55, 65, 72, 80, 88, 94a, 109, 114, 120, 121, 135, 136, 146, 147, 157, 166, 168, 173, 182, 188a, 192, 193a, 202, 204, 212, 220, 227, 242, 245, 256, 260, 267, 270, 275, 280, 310, 312, 327, 330

Bearded collie: 9a, 42, 65, 152, 159a, 166, 245, 256, 269, 270, 303

Bedlington terrier: 2, 23, 42, 88, 94, 184, 199, 210, 223, 256, 265, 266, 269, 270

Belgian malinois: 109, 152, 166, 256

Belgian sheepdog: 42, 109, 152, 166, 204a, 230, 256, 269, 270

Belgian tervuren: 42, 109, 166, 221, 221a, 230, 256

Bernese mountain dog: 20, 42, 46, 47, 54, 55, 103, 149, 149d, 152, 166, 221, 221a, 255, 256, 269, 318

Bichon frise: 42, 53, 65, 103, 109, 122, 148, 235, 331a

Black and tan coonhound: 94, 103, 122, 148, 152, 221, 221a, 252

Bloodhound: 31, 94, 103, 114, 152, 166, 179, 181, 195, 221, 221a, 245, 324

Blue tick hound: 136, 193a, 221, 221a

Border collie: 65, 109, 152, 186, 214, 221, 221a, 256

Border terrier: 17, 39, 42, 58, 68, 70, 126, 145, 186, 196, 217, 235, 248, 256, 270, 324, 327

Borzoi (Russian wolfhound): 31, 36, 42, 118, 152, 155, 166, 192, 200, 256, 312, 330

Boston terrier: 10, 12, 17, 22, 39, 42, 54, 55, 65, 67, 68, 71, 78, 80, 88, 90, 103, 112, 114, 135, 145, 151, 154, 159, 166, 171, 174, 179, 181, 196, 235, 236, 248, 256, 262, 275, 295, 304, 308

Bouvier de Flandres: 42, 55, 74, 90, 94, 100, 103, 131, 135, 152, 166, 221, 221a, 318, 330

Boxer: 3, 6, 10, 22, 24, 38, 42, 67, 72, 75, 80, 83, 88, 94a, 99, 103, 113, 114, 119, 121, 131, 134, 139, 149, 153, 156, 166, 192, 196, 221, 221a, 250, 256, 277, 293, 294, 297, 300, 304a, 312, 317, 325, 330

Briard: 42, 105, 166, 231, 256, 330

Brittany spaniel: 42, 55, 61b, 88, 121, 147, 149b, 186, 221, 221a, 256, 270

Brussels griffon: 1, 42, 88, 256, 278, 281

Bullmastiff: 3, 31, 51, 55, 88, 103, 114, 135, 152, 166, 221, 221a, 245, 256, 270, 273, 280, 325

Bull terrier: 78, 94, 103, 130, 171, 186, 196, 221, 221a, 294, 318, 333

Cairn terrier: 1, 42, 48, 68, 75, 121, 122, 135, 136, 147, 148, 149, 166, 171, 186, 193a, 256, 270, 330

Cardigan Welsh corgi: 61a, 75, 90, 103, 135, 173, 186, 245, 256, 270

Cavalier King Charles spaniel: 37a, 42, 65, 85, 88, 103, 166, 179, 199, 235, 256, 270, 311a

Chesapeake Bay retriever: 42, 88, 103, 114, 152, 221, 221a, 256, 270, 330

Chihuahua: 55, 57, 65, 87, 103, 121, 135, 147, 149, 154, 160, 162, 166, 175, 179, 181, 186, 201, 214, 221, 221a, 235, 256, 260

Chinese shar pei: 10, 22, 29, 80, 94, 103, 128, 129, 135, 152, 166, 168, 172, 186, 187, 221, 221a, 226, 235, 256, 270, 276, 295, 319, 326

Chow chow: 27, 31, 42, 48, 55, 61, 80, 88, 94, 95, 98, 103, 135, 152, 160a, 165, 166, 172, 192, 204, 204a, 221, 221a, 230, 239, 245, 256, 280, 312

Clumber spaniel: 94, 103, 152, 309, 319, 324

Collie: 33, 37, 42, 45, 58, 65, 73, 78, 80, 82, 86, 88, 89, 103, 109, 121, 126, 140, 147, 152, 166, 171, 176, 199, 208, 209, 220, 221, 221a, 236, 238, 245, 256, 270, 273a, 318, 330

Curly-coated retriever: 42, 88, 94, 103, 256

Dalmatian: 10, 22, 32, 78, 80, 81, 88, 103, 129, 130, 135, 136, 140, 152, 166, 193a, 199, 221, 221a, 230, 256, 273a, 294, 321, 322

Dandie Dinmont terrier: 3, 42, 67, 87, 97, 103, 135, 152, 166, 173, 235, 245, 281

Doberman pinscher: 2, 3, 4, 6, 7, 27, 35, 38, 42, 51, 53, 59, 61, 64, 68, 80, 103, 105, 121, 127, 129, 138a, 143a, 146, 147, 152, 161, 166, 170, 173, 182, 192, 199, 206a, 221, 221a, 231, 243, 245, 250, 251, 256, 266, 266a, 267, 270, 292, 304a, 312, 328, 330

English bulldog: 1, 3, 6, 19, 42, 54, 55, 80, 88, 90, 94, 98, 103, 116, 129, 130, 145, 152, 154, 164, 166, 179, 181, 201, 205, 217, 242, 245, 260, 261, 278, 280, 287, 308, 325, 330

English cocker spaniel: 42, 70, 88, 94, 103, 119, 135, 147, 150, 166, 177, 186, 214, 221, 221a, 236, 245, 256, 259, 270, 304, 330

English foxhound: 78, 290

English setter: 31, 42, 61, 68, 78, 91, 94, 103, 121, 124b, 147, 152, 160, 166, 177, 181, 188a, 193a, 214, 221, 221a, 256, 323, 330

English springer spaniel: 9a, 10, 12, 18, 26, 27, 42, 43, 54, 55, 59, 65, 69, 72, 88, 94, 94a, 95, 103, 107, 109, 121, 123, 124, 135, 146, 147, 148, 152, 154, 159a, 160a, 166, 171, 173, 188, 193a, 197, 206a, 220, 221, 221a, 226, 228, 235, 236, 242, 245, 245a, 254, 256, 264a, 266, 270, 275, 276, 286, 307, 318, 319, 320, 330

English toy spaniel (King Charles and Ruby Blenheim spaniels): 42, 55, 65, 85, 103, 143, 235, 270, 318

Field spaniel: 14, 42, 166, 256, 270

Finnish spitz: 85

Flat-coated retriever: 42, 88, 94, 103, 152, 166, 256

French bulldog: 42, 54, 55, 88, 98, 103, 119, 121, 122, 145, 147, 148, 330

German shepherd: 10, 21, 27, 36, 42, 44, 54, 55, 59, 65, 72, 72a, 75, 81, 83, 86, 94a, 95, 102, 103, 105, 109, 112, 114, 121, 122, 129a, 221a, 131, 137, 143a, 147, 148, 152, 166, 168, 180, 186, 191, 192, 193a, 194, 208, 220, 221, 221a, 225, 226, 229, 230, 231, 236, 238, 241, 243, 247, 256, 266, 270, 276, 283, 300, 306, 312, 316, 320, 330

German short-haired pointer: 8, 9a, 42, 65, 103, 114, 124b, 125, 152, 159a, 166, 177, 188a, 191, 193a, 197, 214, 221, 221a, 230, 256, 300, 311, 330

German wire-haired pointer: 42, 103, 152, 221, 221a, 270, 302, 330

Giant schnauzer: 42, 105, 135, 146, 152, 158, 166, 192, 221, 221a, 231, 256, 269, 270, 276, 311a, 312, 327a

Golden retriever: 7, 9, 10, 22, 42, 59, 65, 81, 88, 94, 95, 103, 121, 129, 129a, 130, 140, 143a, 146, 147, 149, 152, 166, 178, 192, 193, 204a, 206, 220, 221, 221a, 256, 273a, 300, 312, 328, 329

Gordon setter: 31, 42, 45, 103, 152, 166, 221, 221a, 256, 179, 181, 270, 307

Great Dane: 6, 7, 31, 36, 38, 42, 48, 50, 51, 61, 75, 78, 80, 83, 88, 94, 103, 114, 131, 135, 144, 152, 153, 155, 158, 166, 176, 192, 198, 199, 201, 204a, 211, 221, 221a, 225, 243, 250, 255, 256, 270, 292, 298, 312, 330

Great Pyrenees: 5, 9, 16, 42, 78, 80, 94, 103, 122, 124, 148, 152, 166, 195, 221, 221a, 244, 256, 304, 311a, 325

Greyhound: 14, 42, 65, 72, 88, 90, 94a, 109, 112, 121, 147, 155, 166, 186, 220, 221, 221a, 230, 245, 256, 279, 326, 330

Harrier: none recognized

Havanese: 42, 245, 256, 269

Ibizan hound: 10, 14, 42, 70, 166, 270, 311a

Irish setter: 7, 10, 22, 31, 40, 42, 61, 65, 79, 81, 88, 103, 109, 121, 129, 130, 131, 132, 138a, 140, 146, 147, 152, 166, 186, 191, 198, 206a, 220, 221, 221a, 243, 245, 256, 264, 273a, 276, 311a, 320, 324, 328, 329

Irish terrier: 75, 85a, 204a, 256

Irish water spaniel: 42, 152, 166, 167, 195, 245, 256, 330

Irish wolfhound: 38, 42, 103, 149, 152, 155, 158, 166, 221, 221a, 330

Italian greyhound: 14, 42, 61, 65, 70, 109, 135, 220, 243, 256, 311a

Jack Russell terrier: 20, 123, 186, 206, 330

Japanese spaniel (Japanese chin): 42, 70, 88, 103, 137, 256

Keeshond: 1, 41, 42, 63, 71, 85, 94, 109, 135, 149, 156, 165, 166, 180, 197, 201, 256, 260, 266, 274, 310, 327, 330

Kerry blue terrier: 42, 47, 88, 103, 124, 141, 166, 179, 181, 207, 256, 311a, 320, 330

Komondor: 42, 103, 152, 166, 285

Kuvasz: 42, 103, 152, 166, 221, 221a, 330

Labrador retriever: 3, 7, 9, 9a, 10, 22, 40, 42, 59, 68, 77, 78, 85, 88, 89, 94, 95, 103, 109, 121, 122, 129a, 147, 148, 149, 152, 158, 159a, 160, 166, 197, 204a, 206a, 221, 221a, 244, 245, 256, 257, 258, 269, 270, 276, 282, 315, 330

Lakeland terrier: 42, 70, 88, 166, 186, 245, 319, 320, 330

Lhasa Apso: 1, 10, 22, 42, 65, 81, 88, 94, 103, 166, 171, 179, 181, 189, 235, 256, 266, 330

Maltese: 1, 30, 70, 78, 88, 110, 135, 149, 152, 160, 166, 192, 235, 256, 270, 312, 330, 331a

Mastiff: 31, 65, 94, 103, 166, 221, 221a, 245, 256, 270, 325

Miniature bull terrier: 103, 166, 186

Miniature dachshund: 4, 5, 42, 43a, 54, 55, 61, 65, 72, 75, 78, 80, 85, 94a, 129, 146, 156, 161, 166, 173, 176, 178, 187, 199, 206a, 214, 216, 224, 228, 230, 237, 239, 250, 256, 267, 275, 296, 297, 326, 328, 330

Miniature pinscher: 42, 65, 87, 103, 140, 171, 179, 181, 185, 230, 256, 273a

Miniature poodle: 5, 10, 22, 26, 27, 42, 49, 78, 81, 88, 92, 93, 103, 109, 110, 111, 121, 135, 136, 140, 144, 147, 156, 165, 166, 173, 175, 184, 193a, 199, 206, 220, 221, 221a, 223, 226, 230, 235, 236, 256, 269, 275, 294, 327, 330

Miniature schnauzer: 10, 22, 42, 70, 76, 88, 103, 112, 121, 144a, 146, 147, 149, 149a, 157, 166, 185, 221, 221a, 259, 260, 266a, 271, 284, 301, 311a, 330

Neapolitan mastiff: 42, 83, 94, 103, 152, 158, 166, 221, 245, 256

Newfoundland: 25, 38, 42, 75, 83, 94, 95, 103, 114, 129a, 146, 152, 166, 183, 192, 221, 221a, 236, 300, 311a, 312, 320, 327, 330

Norwegian dunkerhound: 78, 199,

Norwegian elkhound: 42, 88, 103, 135, 152, 166, 180, 186, 256, 266, 275, 276, 302

Norwich terrier: 65, 166, 186, 330

Nova Scotia duck tolling retriever: 9a, 42, 159a, 166, 256

Old English sheepdog: 9a, 42, 80, 88, 103, 122, 129, 140, 146, 148, 152, 159a, 161, 166, 172, 192, 221, 221a, 250, 256, 269, 270, 273a, 292, 311a, 312, 328, 330

Otter hound: 119, 152, 166, 221, 221a, 249, 274, 311, 330

Papillon: 12, 42, 65, 103, 166, 235, 330

Pekingese: 42, 88, 103, 116, 146, 162, 166, 171, 173, 179, 181, 184, 186, 199, 230, 246, 256, 277, 278, 304, 311a, 317, 318

Pembroke Welsh corgi: 42, 50, 65, 72, 75, 90, 109, 166, 186, 245, 256, 270, 330

Pharoah hound: 10, 166, 220, 311a

Pointer: 8, 10, 36, 42, 65, 80, 89, 103, 109, 152, 166, 178, 213, 215, 230, 231, 239, 256, 318, 330

Pomeranian: 42, 70, 73, 87, 88, 103, 110, 136, 137, 140, 149, 162, 165, 166, 184, 186, 210, 219, 235, 236, 256, 273a, 313

Portuguese water dog: 9a, 42, 88, 159a, 166, 188a, 193a, 245, 256, 273a, 299a

Pug: 10, 22, 50, 54, 57, 65, 67, 76, 80, 81, 90, 98, 98a, 103, 109, 116, 143, 149, 152, 166, 173, 179, 185, 195, 196, 230, 235, 246, 256, 259, 293, 295, 304a, 308, 309, 317

Puli: 27, 42, 152, 256, 270

Rhodesian ridgeback: 42, 45, 51, 84, 103, 152, 166, 221, 221a, 245, 256

Rottweiler: 9a, 27, 42, 85, 88, 94, 95, 103, 105, 129, 129a, 146, 152, 159a, 161, 166, 172, 192, 231, 245, 256, 269, 270, 300, 311a, 312, 326, 328, 330

Saint Bernard: 31, 42, 60, 72, 83, 88, 94, 94a, 103, 109, 114, 118, 121, 122, 133, 147, 148, 149, 152, 166, 188, 198, 221, 221a, 225, 298, 325, 328, 329, 330

Saluki: 14, 27, 42, 65, 103, 146, 166, 214, 245, 256, 269, 270, 311a, 330

Samoyed: 24, 42, 65, 85, 88, 89, 103, 121, 135, 140, 147, 149, 149b, 152, 166, 221, 221a, 242, 245, 256, 260, 269, 270, 273a, 274, 311a, 328, 330

Schipperke: 42, 85, 88, 103, 166, 185, 207, 239, 245, 256

Scottish deerhound: 31, 42, 105, 131, 158, 166, 221, 221a

Scottish terrier: 5, 10, 22, 42, 68, 75, 78, 81, 122, 129, 148, 166, 186, 193, 197, 256, 272, 294, 324, 330

Sealyham terrier: 22, 42, 81, 135, 166, 186, 245, 256, 269, 270

Shetland sheepdog: 5, 42, 52, 59, 65, 82, 86, 88, 108, 121, 122, 129, 147, 148, 149a, 151, 152, 157, 166, 192, 220, 236, 245, 256, 270, 306, 312, 328, 329, 330

Shih Tzu: 1, 42, 54, 55, 83, 88, 89, 94, 103, 146, 149, 166, 182, 187, 256, 266, 269, 311a, 317, 330

Siberian husky: 41, 42, 65, 86, 103, 104, 121, 135, 147, 152, 166, 186, 221, 221a, 230, 245, 256, 270, 328, 329, 330, 334

Silky terrier: 42, 70, 85, 154, 185, 188a, 193a, 235, 245, 256, 311a, 313

Skye terrier: 27, 88, 101, 111, 163, 183, 186, 192, 206, 312, 316, 330

Smooth fox terrier: 3, 10, 22, 42, 78, 81, 87, 88, 112, 135, 138, 166, 185, 186, 221, 221a, 243, 260, 288, 330

Soft-coated Wheaton terrier: 9a, 10, 22, 42, 81, 159a, 166, 172, 220, 245, 253, 256, 266a, 270, 330

Spinoni Italiani: 91, 103

Standard dachshund: 1, 4, 5, 42, 54, 55, 61, 65, 72, 75, 78, 80, 83, 85, 94a, 103, 115, 129, 135, 156, 161, 166, 173, 176, 179, 181, 187, 199, 214, 216, 220, 224, 228, 230, 237, 239, 245, 250, 256, 267, 275, 296, 297, 326, 328, 330

Standard Manchester terrier: 42, 72, 109, 135, 166, 185, 186, 256, 330

Standard poodle: 9a, 10, 21, 22, 27, 31, 42, 61, 81, 88, 103, 109, 110, 121, 124a, 135, 140, 144, 146, 147, 152, 159a, 166, 175, 184, 186, 199, 220, 221, 221a, 223, 230, 245, 256, 269, 273a, 311a, 330

Standard schnauzer: 23, 42, 62, 121, 147, 166, 221, 221a, 240, 260, 270, 330

Sussex spaniel: 38, 42, 88, 103, 270

Swiss mountain dog: 221, 221a, 249, 311, 311a

Tibertan mastiff: 95, 152, 158, 166, 192, 221, 245, 312, 330

Tibetan terrier: 14, 42, 103, 186, 199, 214, 245, 256, 270

Toy Manchester terrier: 42, 166, 186, 256, 330

Toy poodle: 5, 10, 22, 26, 27, 42, 49, 78, 81, 88, 92, 93, 103, 109, 110, 111, 121, 124a, 135, 136, 140, 144, 146, 147, 149, 156, 165, 166, 173, 175, 184, 193a, 199, 221, 221a, 223, 226, 230, 235, 236, 256, 269, 275, 294, 327, 330

Vizsla: 42, 68, 80, 103, 109, 117, 121, 140, 143a, 147, 152, 161, 166, 193, 221, 221a, 256, 273a, 289, 296, 305, 318, 319, 326

Weimaraner: 31, 43a, 61, 65, 88, 103, 105, 114, 121, 131, 140, 142, 147, 152, 158, 160a, 165, 166, 168, 169, 170, 196, 206, 256, 273a, 289, 296, 305, 311b, 318, 319, 326

Welsh springer spaniel: 42, 135, 152, 245, 256

Welsh terrier: 42, 135, 166, 186, 330

West Highland white terrier: 2, 4, 9a, 10, 21, 22, 42, 68, 71, 81, 106, 136, 156, 159a, 171, 181, 185, 186, 199, 245, 270, 276, 331, 331a

Whippet: 42, 61, 70, 80, 103, 143a, 166, 186, 221, 221a, 234, 256, 330

Wire-haired fox terrier: 3, 22, 42, 78, 87, 88, 103, 112, 135, 138, 185, 186, 243, 256, 260, 288, 310, 330

Wire-haired pointing griffon: 152, 206a, 226

Yorkshire terrier: 42, 71, 80, 88, 103, 149, 154, 162, 166, 179, 181, 185, 235, 236, 245, 256, 269, 270, 276, 330

Section II:

1. Aberrant cilia: eyelashes growing abnormally, such as rubbing against the eyeball (see #88).

2. Abnormal copper metabolism: (usually Bedlington terriers or Doberman pinschers) an inability to utilize and store copper properly, resulting in liver disease and other problems.

3. Abnormal dentition: abnormal placement, number and development of teeth.

4. Acanthosis nigricans: (usually dachshunds) a skin disease where the skin becomes thickened and dark, primarily affecting the axillae (armpits).

5. Achondroplasia: abnormal development of cartilage leading to dwarfism (seen aberrantly in most breeds, but that’s what makes a Basset hound and other achondroplastic breeds long and low).

6. Acne: same thing as in humans, affects the muzzle and lip areas.

7. Acral lick dermatitis: a skin disease caused by an animal’s licking a localized area excessively, especially on the legs and paws.

8. Acral mutilation: a progressive self-mutilation of the feet and legs. Also known as peripheral sensory neuropathy in pointing breeds because they are born without pain sensation.

9. Acute moist dermatitis: known as “hot spots,” a localized area of a severely itchy, inflamed and oozing dermatitis exacerbated by the animal’s intense licking and chewing at the spot.

9a. Addison’s disease (hypoadrenocorticism): a disease characterized by inadequate secretion of cortisone from the adrenal glands. More common in Old English sheepdogs, standard poodles and bearded collies. (See #159a.)

10. Allergies: same as in humans. Dogs can be allergic to things they come in contact with, eat or inhale.

11. Amyloidosis: a condition where abnormal deposits of proteinaceous material called amyloid are laid down in tissues and impair their function. Common in Akitas and Chinese shar peis.

12. Anasarca: a condition where neonatal puppies have an abnormal accumulation of fluids in their tissues. Often seen in English bulldogs.

13. Anemia with chondrodysplasia: a condition of Alaskan malamutes where there is malformation and maldevelopment of cartilage and red blood cells. Also called stomatocytosis because of the mouth-like shape of red blood cells.

14. Anesthetic idiosyncracy: a condition where an individual has an abnormal response to commonly used anesthetics sometimes leading to death. Idiosyncratic means there is no good explanation or way to predict this.

15. Anomaly of third cervical vertebra: a malformation of one of the neck bones in the spinal column.

16. Anophthalmia: a condition where an animal is born without any eyes.

17. Aortic body tumors: a cancer that arises from a small organ at the base of the aorta, near the heart.

18. Apocrine gland tumor: a cancer arising from glands which secrete fluids (such as mammary glands).

19. Arteriovenous fistula: an abnormal connection that forms between arteries and veins.

20. Ataxia: (see #255, #288.)

21. Atopic dermatitis: a skin disease caused by a dog’s reaction to an inhalant allergy. (See #81.)

22. Atopy: an allergy caused from things dogs inhale.

23. Atresia of nasolacrimal puncta: a condition where the holes on the inside of the lower eyelids (puncta) are too small or closed so tears spill over the lid instead of draining to the nose.

24. Atrial septal defects: a malformation of the dividing wall between two chambers of the heart, usually resulting in a hole which then causes blood flow abnormalities.

25. Avulsion fractures: fractures of the bones caused by a piece being ripped away, usually because of its strong attachment to a ligament or tendon.

26. Basal cell tumor: a cancer arising from a type of skin cell.

27. Behavioral abnormalities: a whole range of abnormal behavior patterns, such as aggression, panic disorders, etc.

28. Bithoracic ectromelia: a condition where the front leg bones are very small or absent.

29. Blepharospasm: an abnormal tightening of the muscles around the eyes, which causes repetitive blinking.

30. Blindness: an inability to see due to a large variety of causes.

31. Bloat: a condition where a dog’s stomach produces excessive gas and enlarges severely enough to cause death without immediate treatment. Usually associated with gastric torsion (see #131).

32. Blue eyes: an adverse reaction to certain vaccines containing canine hepatitis virus (adenovirus 1) which produces a bluish discoloration to the cornea.

33. Bullous pemphigoid: an autoimmune (i.e., the body attacking itself) disease associated with the formation of painful blisters.

34. Bundle branch block: an abnormality of the electrical conduction mechanism of the heart.

35. Bundle of His degeneration: a condition where a part of the electrical system of the heart deteriorates.

36. Calcinosis circumscripta: the development of lumps of hard calcium deposits in the skin.

37. Cancer, bladder: as in humans, cancer arising from the bladder.

37a. Cardiac valvular disease: weakness of heart valves producing heart murmurs and leading to cardiac failure. Prevalent in Cavalier King Charles spaniels.

38. Cardiomyopathy: a disease of weakened heart muscles. Common in giant breeds, boxers, Doberman pinschers.

39. Carotid body tumors: cancer arising from a small organ located on the carotid in the neck.

40. Carpal subluxation: a condition where the “wrist” bones are loose and out of alignment.

41. Castration responsive dermatosis: a skin condition characterized by loss of hair, thickened skin and inflammatiion which responds to castration (i.e., hormonally dependent).

42. Cataract: as in humans, a change in structure of the lens of the eye leading to cloudiness and usually to blindness.

43. Cataract with microphthalmia: a condition where a dog has cataracts along with abnormally small eyes.

43a. Cell-mediated immunodeficiency: a deficiency of t-lymphocyte function causing impaired immunity, chronic recurrent infections and stunted growth. Seen in Weimaraners and Dachshunds. (See #311b).

44. Cellulitis (folliculitis and furunculosis): inflammation and infection of the cells of the skin including the hair follicles and deeper structures.

45. Cerebellar cortical abiotrophy: malformation of the neurons in the cerebellum, a part of the brain.

46. Cerebellar degeneration: a condition where a part of the brain deteriorates.

47. Cerebellar and extrapyramidal abiotrophy: a condition where the neurons in the cerebellum part of the brain and parts of the spinal cord are malformed and eventually malfunction.

48. Cerebellar hypoplasia: a condition where the cerebellum, a part of the brain, is poorly formed (too small or absent) and doesn’t function properly or at all.

49. Cerebrospinal demyelination: a condition where the neurons of the brain and spinal cord are malformed, lacking a specialized sheath, which causes malfunction.

50. Cervical disc disease: a degeneration or malformation of the cushioning discs between the spinal column bones (vertebrae) in the neck.

51. Cervical vertebral malformation or instability: a malformation of the vertebrae in the neck usually leading to nerve damage. Commonly seen in Doberman pinschers and causes a hackneyed gait (high stepping).

52. Choroidal hypoplasia: improper development of a part of the eye.

53. Ciliary dyskinesia: congenital trait in several breeds where all ciliated cells (those with hairs or moving appendages) are deformed and rigid. Also called immotile cilia syndrome and Kartagener’s syndrome. Causes chronic pneumonia and sterility. Common in bichon frise and Doberman pinschers.

54. Cleft lip: a condition where the two halves of the upper lip do not join together. Cleft palate and cleft lip are often seen together.

55. Cleft palate: a condition where the roof of the mouth is not closed and the inside of the nose opens into the mouth.

56. Coliform enteritis: an inflammation of the bowel tract caused by a certain group of bacteria.

57. Collapsed trachea: a condition where the cartilage rings that make up the trachea are malformed and tend to collapse easily.

58. Collie eye anomaly: a condition of collie dogs where the narrow shape of the head causes the eyes to be malformed.

59. Coloboma: an abnormal development of the eye, usually seen in collies, which can lead to blindness (see #203).

60. Colobomas with aphakia: same as above but with congenital absence of the lens.

61. Color mutant alopecia: a condition where certain colored areas of a dog’s skin grows less or no fur. Commonly seen in Yorkshire terriers, blue Doberman pinschers and fawn Irish setters.

61a. Combined immunodeficiency: a severe combined deficiency of cell-mediated immunity (T-cell function) and low levels of serum immunoglobulins (IgA, IgG, and variably IgM). Affected puppies usually die from viral infectins by 12-16 weeks of age. Seen in Basset hounds. (See 343a, 168, 169, 170.)

61b. Complement deficiency: a deficiency in serum levels of the third component of complement which impairs neutrophil function and causes recurrent infections. Seen in Brittany spaniels.

Continued in Part 2