Genetics

The Shoulder in the Working Dog

Dog breeds are usually grouped—often arbitrarily or erroneously—into from five to ten categories based on function, superficial appearance, or geographical origin, depending on the registry organization. Just because it may make more sense to assign them to groups based primarily on ancestry and then on historical function, does not mean that such will be the …

The Nature of Genetic Disease

Many people label any problem that appears to be inherited a “genetic disease.” However, though there are legitimate genetic diseases, there are also a variety of problems that have an inherited component but are of a fundamentally different nature. Dealing effectively with any genetic problem requires an understanding of …

Eliminating Mutation: The Impossible Dream

Though it is not practical to eliminate all deleterious mutation, the incidence of affected individuals may be significantly reduced through a combination of intelligent breeding practice and the development of DNA tests. Why do we have mutations? Mutations are changes in an organism’s DNA that potentially affect the correct functioning of genes. They occur naturally …

INBREEDING AND DIVERSITY – PART 3

Continued from PART 2 FY = 0. This example emphasizes a point made earlier: inbreeding is dependent on relationship. In small breeds, it often happens that there are a few very influential individuals to whom most of the population is related. These elevated levels of relationship can make it difficult to plan matings free …

Inbreeding and Diversity – Part 5

Continued from PART 4 MORE ON INBREEDING The dog world seems unwilling to learn from science in some respects, and inbreeding-linebreeding is one of those areas. I say “one” because there is no real difference or dividing line between the two terms; linebreeding is simply descriptive of inbreeding on animals a little further back in …